Oral delivery of adeno-associated viral vectors

A - Human Necessities – 61 – K

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Details

A61K 48/00 (2006.01) A01K 67/027 (2006.01) A61K 31/70 (2006.01) C12N 15/864 (2006.01)

Patent

CA 2222574

A method of expressing a gene product in the gut of an animal, which comprises administering a recombinant AAV vector to the gut of the animal, wherein the vector comprises a non-AAV gene of interest ligated into an AAV vector genome.

Selon le procédé d'expression d'un produit génétique dans les intestins d'un animal, on introduit dans les intestins d'un animal un vecteur recombinant d'adénovirus. Le vecteur comprend un gène voulu qui n'est pas un gène d'adénovirus et qui est lié au génome d'un vecteur d'adénovirus.

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