Ngf conjugates and uses thereof

Details Ngf conjugates and uses thereof Ngf conjugates and uses thereof

A - Human Necessities

61

K

A61K 47/48 (2006.01) C07K 14/48 (2006.01)

Patent

CA 2710141

The present invention is in the fields of medicine, public health, immunology, molecular biology and virology. The invention provides composition comprising a virus-like particle (VLP) linked to at least one antigen, wherein said antigen is NGF antigen. The invention also provides a process for producing the composition. The compositions of this invention are useful in the production of vaccines, in particular, for the treatment of pain. Moreover, the compositions of the invention induce efficient immune responses, in particular antibody responses.

La présente invention concerne les domaines de la médecine, de la santé publique, de l'immunologie, de la biologie moléculaire et de la virologie. L'invention concerne une composition comportant une particule de type virus (VLP) liée à un moins un antigène, ledit antigène étant l'antigène NGF. L'invention concerne également un procédé de production de la composition. Les compositions de cette invention sont utiles dans la production de vaccins, en particulier, pour le traitement de la douleur. De plus, les compositions de l'invention induisent des réponses immunitaires efficaces, en particulier des réponses des anticorps.

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