Inhibition of biofilm formation

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) A01N 45/00 (2006.01) A01P 1/00 (2006.01) A61K 31/56 (2006.01) A61P 31/04 (2006.01) C12N 1/20 (2006.01) C12N 15/09 (2006.01) C12Q 1/18 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2573440

The present invention relates to compositions and methods for reducing or inhibiting biofilm comprising modulating expression of a cysB gene in a cell. The invention also provides methods for modulating the expression of a cysB, cysD; cysl, cysD,cysJ, cysK, and ybiK. The invention further provides methods for identifying gene(s) involved in biofilm formation and for identifying biofilm inhibitors.

L'invention concerne des compositions et des procédés permettant de réduire ou d'inhiber un biofilm comprenant une expression de modulation du gène cysB dans une cellule. L'invention concerne également des méthodes permettant de moduler l'expression de cysB, cysD, cysI, cysD,cysJ, cysK, et ybiK. L'invention concerne enfin des méthodes permettant d'identifier un ou des gène(s) impliqué(s) dans la formation d'un biofilm et des inhibiteurs de biofilm.

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