Rnai therapeutics for treatment of eye neovascularization...

C - Chemistry – Metallurgy – 07 – H

Patent

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C07H 21/04 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2555335

Compositions and methods for treating ocular disease are provided. Specifically, siRNA molecules and mixtures of siRNA molecules are provided that inhibit angiogenesis and/or neovascularization in the eye are provided. The compositions and methods are suitable for treating ocular diseases associated with angiogenesis and/or neovascularization.

L'invention porte sur des compositions et sur des méthodes de traitement d'une maladie oculaire. Spécifiquement, l'invention porte sur des molécules de siRNA et des mélanges de ces molécules de siRNA qui inhibent l'angiogenèse et/ou la néovascularisation dans l'oeil. Les compositions et les méthodes de l'invention sont appropriées pour traiter des maladies oculaires associées à l'angiogenèse et/ou la néovascularisation.

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