Tnf-inhibiting proteins and the preparation thereof

Details Tnf-inhibiting proteins and the preparation thereof Tnf-inhibiting proteins and the preparation thereof

C - Chemistry, Metallurgy

07

K

C07K 14/47 (2006.01) A61K 38/17 (2006.01) A61K 38/19 (2006.01) A61P 7/00 (2006.01) A61P 19/08 (2006.01) A61P 37/00 (2006.01) C07K 14/525 (2006.01)

Patent

CA 2425101

Novel proteins which have a molecular weight of about 42,000 daltons and have at the N terminus the amino acid sequence Xaa Thr Pro Tyr Ala Pro Glu Pro Gly Ser Thr Cys Arg Leu Arg Glu where X is hydrogen, a phenylalanine residue (Phe) or the amino acid sequences Ala Phe, Val Ala Phe, Gln Val Ala Phe, Ala Gln Val Ala Phe, Pro Ala Gln Val Ala Phe or Leu Pro Ala Gln Val Ala Phe, and which are suitable for the treatment of diseases, are described.

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