A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/00 (2006.01) A61K 31/713 (2006.01)
Patent
CA 2623391
The present invention is directed to an isolated T-Cell Receptor constant domain and to peptides derived therefrom and recombinant constructs encoding same, effective in therapy of T cell mediated inflammatory disease, autoimmunity and graft rejection. Therapeutic and prophylactic vaccine compositions and methods utilizing these proteins and peptides, DNA vaccines encoding same and T cell vaccines thereof are further provided.
La présente invention a trait à un domaine constant isolé du récepteur de lymphocytes T et à des peptides dérivés de ceux-ci et des constructions recombinantes codant pour lesdits peptides, efficaces pour le traitement de maladie inflammatoire médiée par des lymphocytes T, l'auto-immunité et le rejet de greffe L'invention a également trait à des compositions vaccinales thérapeutiques et prophylactiques et à des procédés utilisant ces protéines et peptides, des vaccins d'ADN codant pour ces protéines et peptides et des vaccins à base de lymphocyte T.
Cohen Irun R.
Quintana Francisco Javier
Cohen Irun R.
Quintana Francisco Javier
Ridout & Maybee Llp
Yeda Research & Development Co. Ltd.
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