Methods for bone healing and fracture repair

Details Methods for bone healing and fracture repair Methods for bone healing and fracture repair

A - Human Necessities

61

K

A61K 31/38 (2006.01) A61K 31/40 (2006.01) A61K 31/4025 (2006.01) A61K 31/445 (2006.01) A61K 31/4535 (2006.01) A61K 31/53 (2006.01) A61K 31/55 (2006.01)

Patent

CA 2198012

A method of facilitating bone healing and fracture repair comprising administering to a human in need thereof an effective amount of a compound having formula (I) wherein R1 and R3 are independently hydrogen, -CH3, (a), ou (b), wherein Ar is optionally substituted phenyl; R2 is selected from the group consisting of pyrrolidine, hexamethyleneimino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.

Le procédé favorisant la guérison osseuse et la consolidation de fractures de la présente invention consiste à administrer à un être humain le nécessitant une quantité efficace d'un composant représenté par la formule générale (I) ou de l'un de ses sels ou solvates pharmaceutiquement acceptables. Dans cette formule générale R?1¿ et R?3¿ sont indépendamment hydrogène, -CH¿3?, (a), ou (b), où Ar est phényle éventuellement substitué. R?2¿ appartient au groupe formé par les pyrrolidine, hexaméthylèneimino et pipéridino.

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