C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2675362
The invention provides compositions and methods for identifying patients for single agent anti-EGFR therapy. The methods comprise determining the genomic polymorphism present in a predetermined region of a gene of interest and correlating the polymorphism to the predictive response. Patients identified as responsive are then treated with the appropriate therapy.
L'invention concerne des compositions et des méthodes permettant d'identifier des patients sensibles à une monothérapie anti-EGFR. Les méthodes consistent: à déterminer le polymorphisme génomique présent dans une région prédéterminée d'un gêne d'intérêt et à corréler le polymorphisme avec la réponse prédictive. Des patients identifiés comme sensibles sont ensuite traités à l'aide de la thérapie appropriée.
Lenz Heinz-Josef
Zhang Wu
Smart & Biggar
University Of Southern California
LandOfFree
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