Polypeptide for treating or preventing adhesions

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/17 (2006.01) A61L 31/10 (2006.01) A61L 31/16 (2006.01) A61L 33/10 (2006.01) A61P 41/00 (2006.01)

Patent

CA 2741302

The described invention provides compositions and methods for treating or preventing adhesions in a subject in need thereof, the method comprising the step of (a) administering an adhesion- reducing amount of a composition comprising a polypeptide having the amino acid sequence YARAAARQ ARAKALARQLGV AA [SEQ ID NO: 1] or a functional equivalent thereof and a carrier. The methods are clinically useful for reducing formation of adhesions initially and for therapeutic treatment of existing scars.

La présente invention concerne des compositions et des procédés pour traiter ou prévenir les adhésions chez un sujet nécessitant ceci, le procédé comprenant létape consistant à (a) administrer une quantité réductrice dadhésion dune composition comprenant un polypeptide ayant la séquence dacides aminés YARAAARQ ARAKALARQLGV AA [SEQ ID NO: 1] ou un équivalent fonctionnel de celui-ci et un véhicule. Les procédés sont cliniquement utiles pour réduire la formation dadhésions initialement et pour le traitement thérapeutique de cicatrices existantes.

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