A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01)
Patent
CA 2638899
A method of making antibody- or antibody fragment-targeted immunoliposomes for the systemic delivery of molecules to treat and image diseases, including cancerous tumors, providing immunoliposomes and compositions, as well as methods of imaging various tissues. The liposome complexes are useful for encapsulation of imaging agents, for example, for use in magnetic resonance imaging. The specificity of the delivery system is derived from the targeting antibodies or antibody fragments.
Cette invention concerne une méthode pour fabriquer des immunoliposomes visant des fragments d'anticorps ou des anticorps pour administration systémique de molécules dans le but de traiter et de produire une image de maladies, y compris des tumeurs cancéreuses. L'invention concerne aussi des immunoliposomes et des compositions, ainsi que des méthodes d'imagerie de divers tissus. Les complexes de liposomes sont utiles pour l'encapsulation d'agents d'imagerie, par exemple, à utiliser en imagerie par résonance magnétique. La spécificité du dispositif d'administration découle du ciblage des anticorps ou des fragments d'anticorps.
Chang Esther H.
Pirollo Kathleen F.
Georgetown University
Osler Hoskin & Harcourt Llp
LandOfFree
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