C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 9/12 (2006.01) C30B 29/58 (2006.01) G01N 23/20 (2006.01) G06F 17/50 (2006.01)
Patent
CA 2378010
An unliganded form of Staphylococcus aureus thymidylate kinase (S. aureus TMK) has been crystallized, and the three dimensional x-ray crystal structure has been solved to 2.3 .ANG. resolution. The x-ray crystal structure is useful for solving the structure of other molecules or molecular complexes, and designing inhibitors of S. aureus TMK activity.
L'invention concerne une forme sans ligand de thymidylate kinase (TMK) de Staphylococcus aureus (S. aureus), qui a été cristallisée, la structure cristalline à rayons X tridimensionnelle ayant une résolution de 2,3 .ANG.. La structure cristalline à rayons X s'utilise pour résoudre la structure d'autres molécules ou complexes moléculaires, et désigner des inhibiteurs de l'activité de la thymidylate kinase (TMK) de S. aureus.
Macrae & Co.
Pharmacia & Upjohn Company
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