A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61P 35/00 (2006.01) C12N 15/11 (2006.01) C12N 15/85 (2006.01)
Patent
CA 2703774
The present invention relates to the field of cancer treatment, particularly to a novel constructs useful for treating tumors expressing H19 and/or IGF-II. More specifically, the invention provides compositions and methods utilizing a nucleic acid construct enabling expression of a cytotoxic gene product directed by more than one tumor specific promoter.
Cette invention relève du domaine des traitements contre le cancer, et concerne, en particulier, de nouveaux constituants utiles pour traiter les tumeurs exprimant H19 et/ou IGF-II. Plus spécifiquement, l'invention concerne des compositions et des procédés utilisant un constituant d'acide nucléique permettant l'expression d'un produit de gène cytotoxique dirigée par plus d'un promoteur spécifique de la tumeur.
Amit Doron
Hochberg Avraham
Ridout & Maybee Llp
Yissum Research Development Company Of The Hebrew University Of
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