Dendrimers for use in targeted delivery

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/48 (2006.01)

Patent

CA 2463974

The present invention provides cationic dendrimers for delivering bioactive molecules, such as polynucleotide molecules, peptides and polypeptides and/or pharmaceutical agents, to a mammalian body. The dendrimers disclosed herein are suitable for targeting the delivery of the bioactive molecules to, for example, the liver, spleen, lung, kidney or heart.

Cette invention a trait à des dendrimères cationiques, destinés à administrer à un organisme mammalien des molécules bioactives, notamment des molécules polynucléotidiques, des peptides ainsi que des polypeptides et/ou des agents pharmaceutiques. Ces dendrimères se prêtent au mieux à une administration ciblée de molécules bioactives, les cibles pouvant être le foie, la rate, les poumons, les reins ou le coeur.

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