A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/415 (2006.01) C07D 231/56 (2006.01)
Patent
CA 2574078
This invention relates to potent potassium channel blocker compounds of Formula (I) or a formulation thereof for the treatment of glaucoma and other conditions which leads to elevated intraoccular pressure in the eye of a patient. This invention also relates to the use of such compounds to provide a neuroprotective effect to the eye of mammalian species, particularly humans.
L'invention porte sur de puissants composés bloqueurs du canal potassique, de formule (I) et sur leurs compositions, utilisables pour le traitement du glaucome et d'autres états entraînant une élévation de la pression intraoculaire. L'invention porte également sur l'utilisation de tels composés pour assurer un effet neuroprotecteur de l'oeil des mammifères, et en particulier de l'homme.
Doherty James B.
Shen Dong-Ming
Merck & Co. Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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