Use of 2 -anilino - 3 , 4 -dihydro - quinazolines as 5ht5a...

Details Use of 2 -anilino - 3 , 4 -dihydro - quinazolines as 5ht5a... Use of 2 -anilino - 3 , 4 -dihydro - quinazolines as 5ht5a...

A - Human Necessities

61

K

A61K 31/517 (2006.01) C07D 239/94 (2006.01)

Patent

CA 2600763

The present invention relates to the use of compounds of formula (I): wherein R1 is hydrogen, lower alkyl or halogen; R2 is hydrogen, lower alkyl, lower alkoxy, halogen, lower alkyl substituted by halogen or cyano; aryl is phenyl, naphthyl or indan-5-yl; n is 1 or 2; and pharmaceutically acceptable acid addition salts thereof for the manufacture of medicaments for the treatment of diseases related to the 5-HT5A receptor.

L~invention concerne l~utilisation de composés de formule (I) : où R1 est un hydrogène, un alkyle inférieur, ou un halogène ; R2 est un hydrogène, un alkyle inférieur, un alkoxy inférieur, un halogène, un alkyle inférieur substitué par un halogène ou un groupement cyano ; aryle est le phényle, le naphtyle, ou le indan-5-yle ; n est 1 ou 2 ; et les sels d~addition d~acide pharmaceutiquement acceptables de ceux-ci, pour la fabrication de médicaments pour le traitement de maladies liées au récepteur 5-HT5A.

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