Improved methods for the preparation of endotoxin-binding...

Details Improved methods for the preparation of endotoxin-binding... Improved methods for the preparation of endotoxin-binding...

C - Chemistry, Metallurgy

07

K

C07K 14/47 (2006.01) C07K 1/18 (2006.01) C07K 19/00 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2136208

Disclosed are improvements in methods for the isolation of endotoxin-binding proteins which are secreted by transfected host cells in appropriate cell culture media, In its preferred embodiment, the invention comprises addition of a canon exchange material to the media as the means of increasing the yield of recombinant endotoxin-binding proteins, such as bactericidal/permeability-increasing protein and lipopolysaccharide-binding protein.

L'invention concerne des amélioratiosn apportées à des procédés d'isolement de protéines fixant l'endotoxine sécrétées par des cellules hôtes transfectées dans des milieux de culture appropriés. Dans un mode préféré de réalisation, le procédé consiste à ajouter un matériau échangeur de cations dans ledit milieu afin d'augmenter le rendement des protéines recombinées fixant l'endotoxine telles que la protéine bactéricide/augmentant la perméabilité et la protéine fixant les lipopolysaccharides.

Affiliated with

Also associated with

Rating

Improved methods for the preparation of endotoxin-binding... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Improved methods for the preparation of endotoxin-binding..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Improved methods for the preparation of endotoxin-binding... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1819316