Trisubstituted phenyl derivatives as selective...

Details Trisubstituted phenyl derivatives as selective... Trisubstituted phenyl derivatives as selective...

C - Chemistry, Metallurgy

07

C

C07C 233/75 (2006.01) A61K 31/165 (2006.01) A61K 31/235 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) C07C 233/29 (2006.01) C07C 235/46 (2006.01) C07C 235/56 (2006.01) C07C 323/42 (2006.01) C07D 207/456 (2006.01) C07D 213/75 (2006.01) C07D 213/81 (2006.01) C07D 239/42 (2006.01) C07D 241/20 (2006.01)

Patent

CA 2114114

Compounds of formula (1) are described wherein Y represents a halogen atom or a group -OR1 where R1 represents an optionally substituted alkyl group; R2 represents an optionally substituted cycloalkyl, cycloalkenyl or polycycloalkyl group; Z represents -N(R3)CO- or -CONE(R3) represents a hydrogen atom or an alkyl, aryl or aralkyl group; R4 represents an aryl or heteroaryl group; X represents -O-, -S-, -CH2- or -N(R5)-, where R5 is a hydrogen atom or an alkyl group; n is zero or an integer or value 1, 2 or 3; and the salts, solvates and hydrates thereof. The compounds are selective phosphodiesterase IV inhibitors and are useful for the prophylaxis or treatment of inflammatory diseases.

Affiliated with

Also associated with

Rating

Trisubstituted phenyl derivatives as selective... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Trisubstituted phenyl derivatives as selective..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Trisubstituted phenyl derivatives as selective... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1821072