A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/575 (2006.01) A61K 9/08 (2006.01) A61K 47/36 (2006.01) A61P 39/00 (2006.01)
Patent
CA 2584184
The present disclosure is related to clear aqueous solutions of one or more bile acids and either an aqueous soluble starch conversion product or a non- starch polysaccharide. Solutions of the disclosure may be administered to a subject in conjunction with a pharmaceutical compound having one or more toxic effects. In some embodiments, solutions of the disclosure are administered to a mammal in conjunction with a pharmaceutical compound associated with a peripherial neurotoxicity (e.g., cisplatin and/or suramin) to reduce or eliminate the neuropathic effect(s).
L'invention concerne des solutions aqueuses transparentes constituées d'au moins un acide biliaire et soit d'un produit de conversion d'amidon soluble aqueux ou d'un polysaccharide sans amidon. Les solutions de l'invention peuvent être administrées à un patient conjointement à un composé pharmaceutique présentant au moins un effet toxique. Dans certains modes de réalisation de l'invention, les solutions sont administrées à un mammifère conjointement à un composé pharmaceutique associé à une neurotoxicité périphérique (par exemple, cisplatine et/ou suramine) pour réduire ou pour éliminer l'effet ou les effets neuropathiques.
Kirby Eades Gale Baker
Yoo Seo Hong
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