Process for preparing acetoxyazetidinone derivative and...

Details Process for preparing acetoxyazetidinone derivative and... Process for preparing acetoxyazetidinone derivative and...

C - Chemistry, Metallurgy

07

D

C07D 205/08 (2006.01) C07C 227/18 (2006.01) C07C 227/32 (2006.01) C07C 229/22 (2006.01) C07D 239/70 (2006.01) C07D 265/12 (2006.01) C07D 265/22 (2006.01) C07D 279/08 (2006.01) C07D 413/06 (2006.01) C07F 7/10 (2006.01) C07F 7/18 (2006.01)

Patent

CA 2190408

The present invention is directed to an N-[2-(1-hydroxyethyl)-3- oxopropyl]amine compound of the formula [III]: Image [III] wherein Ring B represents a benzene ring which may be substituted; W represents an oxygen atom or sulfur atom; Y represents an oxygen atom, sulfur atom or NR0,R0 represents hydrogen atom or a substituent; Z represents a substituted methylene group which contains at least one chiral center; R5 represents an aralkyloxycarbonyl group or an alkoxycarbonyl group; R6 represents hydrogen atom, an aralkyl group, an acyloxy group, a tri-substituted silyoxy group or an alkoxy group; or both of R5 and R6 bond at their termini and combine with the adjacent nitrogen atom to form phthalimido group, and a process thereof. Said compound [III] is useful as a starting compound of .beta.-lactam antibacterial agents.

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