Epitopes of shigella like toxin and their use as vaccine and...

Details Epitopes of shigella like toxin and their use as vaccine and... Epitopes of shigella like toxin and their use as vaccine and...

C - Chemistry, Metallurgy

07

K

C07K 14/425 (2006.01) A61K 39/108 (2006.01) A61K 39/112 (2006.01) C07K 14/245 (2006.01) C07K 14/25 (2006.01) C07K 16/12 (2006.01) G01N 33/68 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2295940

The present invention concerns immunogenic epitopes of Shigella-like toxins (SLTs), particularly the Shigella-like toxin of E.coli O157:H7, their use as immunogens and in treatment or diagnosis, agents (for example antibodies and antigen-binding fragments) which specifically neutralise them, their use in treatment and diagnosis, and methods for same.

L'invention concerne des épitopes immunogènes de toxines de type Shigella (SLT), plus particulièrement la toxine de type Shigella de E. coli O157:H7, leur utilisation en tant qu'immunogènes et dans le traitement ou le diagnostic, des agents (par exemple des anticorps et des fragments antiliants) qui les neutralisent, leur utilisation dans le traitement et le diagnostic, ainsi que des procédés de préparation.

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