1-aryl-2-(1h-1,2,4-triazol-1-yl) ethanol derivative and...

Details 1-aryl-2-(1h-1,2,4-triazol-1-yl) ethanol derivative and... 1-aryl-2-(1h-1,2,4-triazol-1-yl) ethanol derivative and...

C - Chemistry, Metallurgy

07

D

C07D 403/14 (2006.01) A61K 31/50 (2006.01) A61K 31/715 (2006.01) C07D 521/00 (2006.01) C08B 37/18 (2006.01)

Patent

CA 2087824

ABSTRACT OF THE DISCLOSURE (+)-2-(2,4-Difluorophenyl)-3-methyl-1-(1H-1,2,4- triazol-1-yl)-3-(6-(1H-1,2,4-triazol-1-yl)pyridazin-3- ylthio)butan-2-ol and a pharmaceutically acceptable salt thereof useful as an antifungal agent are disclosed. An inclusion complex of the compound with cyclodextrin can be given either orally or intravenously and has increased absorption when administered orally. - 43 -

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