Triaryl-oxy-aryloxy-pyrimidine-2,4,6-trione...

Details Triaryl-oxy-aryloxy-pyrimidine-2,4,6-trione... Triaryl-oxy-aryloxy-pyrimidine-2,4,6-trione...

C - Chemistry, Metallurgy

07

D

C07D 413/14 (2006.01) A61K 31/515 (2006.01) C07D 403/12 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2484067

The present invention relates to triaryl-oxy-aryloxy-pyrimidine-2,4.6-trione; metalloproteinase inhibitors of the formula wherein X, A, Y, B, G, W. and R1 are as defined in the specification, and to pharmaceutical compositions and methods of treating inflammation, cancer and other disorders.

L'invention concerne des inhibiteurs de métalloprotéinase triaryl-oxy-aryloxy-pyrimidine-2,4,6-trione selon la formule (I), dans laquelle X, A, Y, B, G, W, et R?1¿ sont tels que définis dans le descriptif, ainsi que des compositions pharmaceutiques et des procédés permettant de traiter des inflammations, le cancer et d'autres troubles.

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