A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 27/00 (2006.01) A61F 2/28 (2006.01) A61L 27/02 (2006.01) A61L 27/10 (2006.01) A61L 27/12 (2006.01) A61L 27/38 (2006.01) C03B 19/08 (2006.01) C03C 4/00 (2006.01) C03C 11/00 (2006.01) C12N 5/00 (2006.01) C12N 5/06 (2006.01) C12N 11/14 (2006.01) A61F 2/00 (2006.01)
Patent
CA 2142282
2142282 9404657 PCTABS00030 Novel non-crystalline, porous bioactive glass and ceramic materials that permit the in vitro formation of bone tissue when exposed to a tissue culture medium and inoculated with cells are disclosed. The present invention also discloses methods of treating bioactive glass materials to control pH so that when the glass is exposed to a tissue culture medium and then inoculated with cells, bone tissue growth occurs in vitro. The glass material disclosed is preferably formed from SiO2, CaO, Na2O and P2O5 and the porous, non-crystalline structure is most preferably created by melting the constituents, cooling and pulverizing the resulting glass, and then forming and hot pressing the powder. The glass of the present invention may be formed to produce templates that are useful for various indications, as well as granules that may be formed into a paste.
Ducheyne Paul
El-Ghannam Ahmed
Shapiro Irving
Smart & Biggar
The Trustees Of The University Of Pennsylvania
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