Human neutrophil elastase inhibitors

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 5/062 (2006.01) A61K 31/41 (2006.01) A61K 31/535 (2006.01) A61K 38/05 (2006.01) C07D 249/08 (2006.01) C07D 271/06 (2006.01) C07D 271/10 (2006.01) C07D 285/08 (2006.01) C07D 401/00 (2006.01) C07D 403/00 (2006.01) C07D 409/00 (2006.01) C07D 413/00 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/00 (2006.01) C07D 417/12 (2006.01) C07K 5/02 (2006.01) C07K 5/06 (2006.01) C07K 5/065 (2006.01) C07K 5/068 (2006.01) C07K 5/072 (2006.01) C07K 5/078 (2006.01) C07K 5/083 (2006.01) C07K 5/12 (2006.01

Patent

CA 2205198

The present invention relates to certain substituted oxadiazole, thiadiazole and triazole peptoids which are useful as inhibitors of serine proteases including human neutrophil elastase, equivalently known as human leukocyte elastase.

La présente invention concerne certains peptoïdes oxadiazole, thiadiazole et triazole substitués, utilisés comme inhibiteurs des sérine-protéase, y compris l'élastase neutrophile humaine, connue également sous le nom d'élastase leucocytaire humaine.

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