C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 207/14 (2006.01) C07D 207/16 (2006.01) C07D 477/00 (2006.01) A61K 31/407 (2006.01) A61P 31/04 (2006.01)
Patent
CA 2602097
A synthetic pathway to produce carbapenem antibacterial agents at low cost with high safety, which pathway is suitable for mass production thereof. There is provided a process for producing carbapenem antibacterial agents with the use of amine compound (1) or salt thereof as a production intermediate: wherein R1 is a C1-C3 alkyl; n is 0, 1 or 2; A is a C1-C3 alkylene; L is an eliminable group; and R3 is a hydrogen atom, a C1-C3 alkyl or an amino protective group, provided that the hydroxyl and carboxyl each independently may be protected.
Méthode de synthèse à faible coût d~agents antibactériens carbapenem, présentant une grande sûreté et étant adaptée à la production de masse de ces agents. L~invention concerne un procédé de fabrication d~agents antibactériens carbapenem, à l~aide d~un composé aminé (1) ou d~un de ses sels comme produit intermédiaire : où R1 est un alkyle en C1-C3; n est 0, 1 ou 2 ; A est un alkylène en C1-C3 ; L est un groupement éliminable ; et R3 est un atome d~hydrogène, un alkyle en C1-C3 ou un groupement protecteur aminé, à condition que l~hydroxyle et le carboxyle puissent chacun être protégés indépendamment.
Hayashi Masaki
Kobayashi Satoshi
Michida Makoto
Daiichi Sankyo Company Limited
Marks & Clerk
LandOfFree
Process for producing carbapenem derivatives having... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Process for producing carbapenem derivatives having..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for producing carbapenem derivatives having... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1827249