Aryl and heteroaryl propene amides, derivatives thereof and...

Details Aryl and heteroaryl propene amides, derivatives thereof and... Aryl and heteroaryl propene amides, derivatives thereof and...

C - Chemistry, Metallurgy

07

C

C07C 233/09 (2006.01) A61K 31/165 (2006.01) A61K 31/195 (2006.01) C07C 229/00 (2006.01) C07C 233/44 (2006.01) C07C 235/38 (2006.01) C07C 237/20 (2006.01) C07C 255/57 (2006.01)

Patent

CA 2497060

Compounds useful as antiproliferative agents, radioprotective agents and cytoprotective agents, including, for example, anticancer agents, are provided according to formula I : wherein ring A, ring B,~~~~,X, R1, R2, R3, a, and b are as defined herein.

La présente invention se rapporte à des agents antiprolifératifs, des agents radioprotecteurs et des agents cytoprotecteurs comprenant, par exemple, des agents anticancéreux. Les composés selon l'invention sont représentés par la formule 1 dans laquelle l'anneau A, l'anneau B,^^^^, X, R?1¿, R?2¿,? ¿R?3¿,? ¿a, et b sont tels que définis dans le descriptif. Formule 1

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