Synergistic combination comprising roflumilast and a pde-3...

Details Synergistic combination comprising roflumilast and a pde-3... Synergistic combination comprising roflumilast and a pde-3...

A - Human Necessities

61

K

A61K 31/44 (2006.01) A61K 31/415 (2006.01) A61K 31/4166 (2006.01) A61K 31/444 (2006.01) A61K 31/501 (2006.01) A61K 45/00 (2006.01) A61K 45/06 (2006.01) A61P 9/00 (2006.01) A61P 11/00 (2006.01) A61P 11/06 (2006.01) A61P 11/08 (2006.01) A61P 29/00 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2372850

The invention relates to the combined use of the PDE4 inhibitor N- (3,5- dichloropyrid-4-yl)- 3-cyclopropylmethoxy- 4-difluoromethoxybenzamide, its pharmacologically tolerable salts or its N- oxide with a PDE3 inhibitor for the treatment of certain disease conditions such as, for example, acute or chronic obstructions of the bronchi.

L'invention concerne l'utilisation combinée de l'inhibiteur de la PDE4, N-(3,5-dichloropyrid-4-yl)-3-cyclopropylméthoxy-4-difluorométhoxybenzamide, de ses sels pharmaceutiquement tolérables ou de ses oxydes de N, avec un inhibiteur de la PDE3 pour le traitement de certains états pathologiques tels que, par exemple, des obstructions chronique ou aiguë des bronches.

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