Glucoamylase variants with altered properties

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 9/34 (2006.01) C07K 14/37 (2006.01) C12N 15/31 (2006.01) C12N 15/56 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2702024

The present invention relates to variant glucoamylases wherein the variant has altered properties (e.g., improved thermostability and/or specific activity) compared to a corresponding parent glucoamylase. The present invention also relates to enzyme compositions comprising a variant glucoamylase (e.g., starch hydrolyzing compositions); DNA constructs comprising polynucleotides encoding the variants and methods of producing the variant glucoamylases in host cells

La présente invention concerne des variants de glucoamylase, lesdits variants ayant des propriétés modifiées (par exemple une meilleure stabilité thermique et/ou une activité spécifique accrue) par rapport à une glucoamylase parente correspondante. La présente invention concerne également des compositions enzymatiques contenant un variant de glucoamylase (par exemple des compositions hydrolysant l'amidon); des constructions d'ADN contenant des polynucléotides codant pour les variants et des procédés de production des variants de glucoamylase dans des cellules hôtes.

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