A - Human Necessities – 61 – M
Patent
A - Human Necessities
61
M
A61M 15/00 (2006.01) A61B 5/087 (2006.01) A61B 5/091 (2006.01) A61M 16/00 (2006.01)
Patent
CA 2194774
A method of drug delivery is disclosed wherein a patient's inspiratory flow rate and inspiratory volume are simultaneously measured using a portable, hand held, device which may be electronic and battery powered or mechanical. Information obtained from the measurement is used to release into a patient's inspiratory flow path, particles of a pharmaceutically active drug. The released particles have a particle size in the range of from about 0.5 microns to 12 microns. The drug is released when the patient's measured inspiratory flow rate is in the range of from about 0.10 liters/second to about 2.0 liters/second, and the patient's inspiratory volume is in the range of from about 0.15 liters to about 0.8 liters.
On décrit un procédé de diffusion de médicaments qui permet de mesurer simultanément le débit et le volume inspiratoires d'un patient avec un dispositif à main portable qui peut être électronique, alimenté par piles ou mécanique. Les informations provenant de ces mesures permettent de diffuser, dans une voie inspiratoire du patient, des particules d'une substance pharmacologiquement active. Les particules diffusées présentent une taille de 0,5 à 12 microns environ. Le médicament est diffusé quand le débit inspiratoire mesuré du patient varie entre 0,1 et 2 litres/seconde environ, et quand son volume inspiratoire varie entre 0,15 et 0,8 litres environ.
Lloyd Lester J.
Rubsamen Reid M.
Aradigm Corporation
Smart & Biggar
LandOfFree
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