Antithrombotic substituted cycloalkano[b]dihydroindole- and...

Details Antithrombotic substituted cycloalkano[b]dihydroindole- and... Antithrombotic substituted cycloalkano[b]dihydroindole- and...

C - Chemistry, Metallurgy

07

D

167/240, 260/317

C07D 209/82 (2006.01) A61K 31/40 (2006.01) C07D 209/88 (2006.01) C07D 209/94 (2006.01)

Patent

CA 2028621

ABSTRACT OF THE DISCLOSURE Substituted antithrombotic substituted cycloalkano[b]- dihydroindole- and -indole-sulphonamides for treatment of thromboses, thromboembolisms, ischaemias, asthma and allergies, of the formula Image (I) in which R1, R2, R3 and R4 are hydrogen or other radicals, X is aryl, alkyl or CF3, m and Z each is 1,2,3 or 4, n is 0,1 or 2, A is a bond or -NH-, and Y is OH, alkoxy, aryloxy, amino or sulphonylamine, with the proviso that, in all cases, two of the substi- tuents R1-R4 are other than hydrogen in the event that m represents the number 2 and Y represents the hydroxyl group, or a salt thereof, Le A 27 157

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