C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/00 (2006.01) A61K 31/505 (2006.01) C07D 239/69 (2006.01) C07D 401/04 (2006.01) C07D 401/14 (2006.01) C07D 403/10 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01) C07D 473/00 (2006.01)
Patent
CA 2208018
Compounds of formula (I) wherein R1-R8, A and B have the significance given in the description, are endothelin inhibitors and can be used for the treatment of disorders which are associated with endothelin activities, such as high blood pressure.
Des composés de formule (I), où R<1>-R<8>, A et B ont la notation donnée dans le descriptif, sont des inhibiteurs de l'endothéline et peuvent s'utiliser pour le traitement de troubles associés aux activités de l'endothéline, tels que l'hypertension artérielle.
Breu Volker
Burri Kaspar
Cassal Jean-Marie
Clozel Martine
Hirth Georges
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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