A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01) A61K 38/18 (2006.01) A61K 47/38 (2006.01)
Patent
CA 2711114
Aspects of this invention relate to compositions and methods for the stabilization, storage, and delivery of biologi-cally active agents, in particular peptides and nucleic acids. Particularly preferred embodiments include compositions that com-prise a recombinant naturally occurring human hepatocyte growth factor (HGF), such as dHGF, a five amino acid truncated HGF variant, and at least one monoglyceride that remains in crystalline form at body temperature. Optionally, a gelling agent such as, hydroxyethylcellulose, and/or an antipathogenic compound (e.g., bupivacaine) can be included in the composition. Methods of use of these compositions to improve, ameliorate, or treat skin conditions are also embodiments.
L'invention porte, selon certains aspects, sur des compositions et des procédés pour la stabilisation, le stockage et l'administration d'agents biologiquement actifs, en particulier de peptides et d'acides nucléiques. Des modes de réalisation particulièrement préférés englobent des compositions qui comprennent un facteur de croissance d'hépatocytes (HGF) humain d'origine naturelle, recombinant, tel que le dHGF, un variant de HGF tronqué de cinq acides aminés, et au moins un monoglycéride qui reste sous forme cristalline à la température corporelle. Facultativement, un agent de gélification, tel que l'hydroxyéthylcellulose et/ou un composé antipathogène (par exemple, la bupivacaïne), peut être compris dans la composition. L'invention porte également sur des procédés d'utilisation des ces compositions pour guérir, améliorer ou traiter des affections cutanées.
Kringle Pharma Inc.
Sim & Mcburney
LandOfFree
Topical compositions for the controlled delivery of proteins... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Topical compositions for the controlled delivery of proteins..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Topical compositions for the controlled delivery of proteins... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1830493