Method for retaining ophthalmological agents in ocular tissues

Details Method for retaining ophthalmological agents in ocular tissues Method for retaining ophthalmological agents in ocular tissues

A - Human Necessities

61

K

167/194, 167/199

A61K 31/715 (2006.01) A61K 9/00 (2006.01) A61K 31/335 (2006.01) A61K 31/57 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2037624

28064-4 ABSTRACT OF THE DISCLOSURE Disclosed is a medicament for treating an ocular tissue, which comprises (i) an ophthalmologically acceptable diluent and (ii) an effective amount of a complex of an ophthalmological agent and a glucan sulfate, the ophthalmological agent in the complex form being retained at the ocular tissue better than the uncomplexed form. The glucan sulfate such as cyclodextrin sulfate binds the ocular tissue and is used as a vehicle for transporting and keeping the ophthalmological agent in eyes at high concentrations.

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