Substituted cyclopentanes having prostaglandin activity

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 405/00 (2006.01) A61K 31/047 (2006.01) A61K 31/192 (2006.01) A61P 27/02 (2006.01) A61P 27/06 (2006.01)

Patent

CA 2713958

11,15, 19-trihydroxy-9-halo-prostaglandin analogues and its use as ocular hypotensive agents. Ocular hypotensive agents are useful in the treatment of a number of various ocular hypertensive conditions, such as post-surgical and post-laser tra-beculectomy ocular hypertensive episodes, glaucoma, and as presurgical adjuncts.

L'invention porte sur des analogues de 11,15,19-trihydroxy-9-halo-prostaglandine et sur leur utilisation en tant qu'agents hypotenseurs oculaires. Les agents hypotenseurs oculaires sutilisent dans le traitement d'un certain nombre de divers troubles hypertenseurs oculaires, tels que des épisodes hypertenseurs oculaires dus à une trabéculectomie postopératoire et post-laser, un glaucome et en tant qu'adjuvants préopératoires.

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