C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 9/38 (2006.01)
Patent
CA 2197267
A process is provided for the preparation of 4-amino-1-hydroxybutylidene- 1,1-bisphosphonic acid or salts thereof which comprises of: a) reacting 4-aminobutyric acid with phosphorous acid and phosphorus trichloride in the presence of a polyalkylene(glycol); and b) recovering said 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid or salts thereof.
Kubela Rudolf
Tao Yong
Apotex Inc.
Apotex Technologies Inc.
Mckinnon Graham J.k.
LandOfFree
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