Piperidine derivatives as antihistaminics

Details Piperidine derivatives as antihistaminics Piperidine derivatives as antihistaminics

C - Chemistry, Metallurgy

07

D

260/292.2, 260/2

C07D 211/06 (2006.01) C07D 401/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2010749

NEW PIPERIDINE DERIVATIVES AS ANTIHISTAMINICS SUMMARY: New antihistaminic piperidine derivatives of general structural formula I are prepared by reacting 4- piperidinealkylamines with carboxylic acids or their active derivatives, such as lower-alkyl esters or the acid chlorides. The obtained new piperidine carboxamide compounds show potent antihistaminic activity as specific antagonists of histamine H1-receptors. Image I

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