Simultaneous dual isotope imaging of cardiac perfusion and...

A - Human Necessities – 61 – K

Patent

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Details

A61K 51/04 (2006.01) A61K 51/12 (2006.01) C07C 323/41 (2006.01) C07D 213/64 (2006.01) C07D 213/71 (2006.01) C07D 213/74 (2006.01) C07D 213/77 (2006.01) C07D 213/82 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 405/04 (2006.01) C07D 405/10 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01)

Patent

CA 2427911

The present invention provides novel diagnostic compositions comprising a radiolabeled LTB4 binding agent and a radiolabeled perfusion imaging agent, diagnostic kits comprising such compositions, and methods of concurrent imaging in a mammal comprising administering a radiolabeled LTB4 binding agent and a radiolabeled perfusion imaging agent, and concurrently detecting the radiolabeled LTB4 binding agent bound at the LTB4 receptor and the radiolabeled perfusion imaging agent.

L'invention concerne de nouvelles compositions diagnostiques renfermant un agent de liaison LTB4 radiomarqué et un agent de visualisation de perfusion radiomarqué, des kits diagnostiques comprenant ces compositions, et des procédés d'imagerie concurrente chez un mammifère consistant à administrer un agent de liaison LTB4 radiomarqué et un agent de visualisation de perfusion radiomarqué, et parallèlement à détecter l'agent de liaison LTB4 radiomarqué lié au récepteur LTB4 et l'agent de visualisation de perfusion radiomarqué.

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