Pns cell lines and methods of use therefor

Details Pns cell lines and methods of use therefor Pns cell lines and methods of use therefor

C - Chemistry, Metallurgy

12

N

C12N 5/0797 (2010.01) C12N 5/0735 (2010.01) C12N 5/0793 (2010.01) C12N 5/10 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2325603

Conditionally-immortalized PNS progenitor cell lines are provided. Such cell lines, which may be clonal, may be used to generate neurons. The cell lines and/or differentiated cells may be used for the development of therapeutic agents to prevent and treat a variety of PNS-related diseases. The cell lines and/or differentiated cells may also be used in assays and for the general study of PNS cell development, death and abnormalities.

L'invention porte sur des lignées de cellules progénitrices du SNP (système nerveux périphérique) conditionnellement immortalisées, éventuellement obtenues par clonage, et pouvant servir à générer des neurones. Les lignées de cellules et/ou de cellules différentiées, qui peuvent servir à développer des agents thérapeutiques prévenant et traitant différentes maladies touchant au SNP, peuvent également servir à des essais, et à l'étude générale du développement, de la mort et des anomalies des cellules du SNP.

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