Compositions for and methods of enhancing the immune...

A - Human Necessities – 61 – K

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A61K 31/7032 (2006.01) A61K 39/00 (2006.01) A61K 39/39 (2006.01) A61P 37/04 (2006.01) C07D 309/10 (2006.01) C07H 5/06 (2006.01)

Patent

CA 2708246

Compositions comprising the compound of formula are provided herein. Also provided are methods of enhancing an immune response of a subject to an antigen by administering the antigen and the composition. The enhanced immune response may be an humoral immune response, a CD4+ T cell response, a CD8+ T cell response or result in activation of antigen presenting cells Methods of enhancing the immune response by intramuscular administration of an antigen and the composition including the compound of formula I are also provided.

L'invention porte sur des compositions contenant le composé représenté par la formule. L'invention porte également sur des procédés pour améliorer une réponse immunitaire d'un sujet contre un antigène par l'administration de l'antigène et de la composition. La réponse immunitaire améliorée peut être une réponse immunitaire humorale, une réponse des lymphocytes T CD4+, une réponse des lymphocytes T CD8+, ou peut conduire à l'activation de cellules présentant des antigènes. L'invention porte également sur des procédés d'amélioration de la réponse immunitaire par administration intramusculaire d'un antigène et de la composition contenant le composé représenté par la formule I.

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