Spirocycles as inhibitors of 11-beta hydroxyl steroid...

Details Spirocycles as inhibitors of 11-beta hydroxyl steroid... Spirocycles as inhibitors of 11-beta hydroxyl steroid...

C - Chemistry, Metallurgy

07

D

C07D 471/10 (2006.01) A61K 31/444 (2006.01) A61P 3/04 (2006.01)

Patent

CA 2691150

The present invention relates to certain spirocyclic compounds that are inhibitors of 11- hydroxyl steroid dehydrogenase type 1 (11 HSD1), compositions containing the same, and methods of using the same for the treatment of diabetes, obesity and other diseases.

La présente invention concerne certains composés spirocycliques qui sont des inhibiteurs de la 11-ß-hydroxy-stéroïde déshydrogénase de type 1 (11 HSD1), des compositions les contenant et des procédés les utilisant pour le traitement du diabète, de l'obésité et d'autres maladies.

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