Carbon linked modulators of .gamma.-secretase

Details Carbon linked modulators of .gamma.-secretase Carbon linked modulators of .gamma.-secretase

C - Chemistry, Metallurgy

07

C

C07C 57/42 (2006.01) A61K 31/192 (2006.01) A61P 25/28 (2006.01) C07C 57/58 (2006.01) C07C 57/60 (2006.01) C07C 59/56 (2006.01) C07C 59/88 (2006.01) C07C 255/57 (2006.01) C07D 213/61 (2006.01)

Patent

CA 2702959

The present invention relates to compounds of Formula (I) as shown below, wherein the definitions of A, X, R1, R3, R4, R5, R6, R7, R8, and R9 are provided in the specification. Compounds of Formula (I) are useful for the treatment of diseases associated with y-secretase activity, including Alzheimer's disease.

La présente invention porte sur des composés représentés par la formule (I) telle que représentée ci-après, dans laquelle les définitions de A, X, R1, R3, R4, R5, R6, R7, R8 et R9 sont fournies dans la description. Les composés de Formule (I) sont utiles pour le traitement de maladies associées à l'activité de la ?-sécrétase, comprenant la maladie d'Alzheimer.

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