Hydrogenation method for producing optically active alcohols...

C - Chemistry – Metallurgy – 07 – C

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C07C 29/149 (2006.01) C07C 31/22 (2006.01) C07C 213/00 (2006.01) C07C 215/08 (2006.01) C07D 307/33 (2006.01)

Patent

CA 2553700

The invention concerns a method for producing optically active hydroxy-, alkoxy-, amino-, alkyl-, aryl- or chlorine-substituted alcohols or hydroxycarboxylic acids having 3 to 25 carbon atoms or their acid derivatives or cyclization products by hydrogenating the correspondingly substituted optically active monocarboxylic acids or dicarboxylic acids or their acid derivatives in the presence of a catalyst whose active constituent contains a noble metal selected from the group of metals consisting of Pt, Pd, Rh, Ir, Ag, Au and at least one additional element selected from the group of elements consisting of Sn, Ge, Mo, W, Ti, Zr, V, Mn, Fe, Co, Ni, Cu, Zn, Ga, In, Pb, Bi, Cr, Ce, Pr, Nd, Pm, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb and Lu.

L'invention concerne un procédé permettant de produire des alcools substitués par hydroxy, alcoxy, amino, alkyle, aryle ou chlore ou des acides hydroxycarboxyliques ayant entre 3 et 35 atomes de carbone, optiquement actifs ou leurs dérivés acides ou leurs produits de cyclisation, par hydrogénation des acides mono- ou des dicarboxyliques optiquement actifs substitués de manière appropriée ou leurs dérivés acides, en présence d'un catalyseur dont le constituant actif contient un métal noble sélectionné dans le groupe des métaux Pt, Pd, Rh, Ir, Ag, Au et au moins un autre élément sélectionné dans le groupe des éléments suivants : Sn, Ge, Mo, W, Ti, Zr, V, Mn, Fe, Co, Ni, Cu, Zn, Ga, In, Pb, Bi, Cr, Ce, Pr, Nd, Pm, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb et Lu.

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