A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) C12N 15/88 (2006.01)
Patent
CA 2595704
Compositions and methods for preventing or inhibiting the growth of a hyperproliferative lesion in a subject that include a nucleic acid comprised in a solid or semi¬ solid formation or in a transdermal or transcutaneous delivery device are disclosed. Also disclosed are compositions of a nucleic acid capable of preventing or inhibiting the growth of a hyperproliferative lesion in a subject that include an adhesive. Compositions of a nucleic acid capable of preventing or inhibiting the growth of a hyperproliferative lesion in a subject that include a nucleic acid uptake enhancer are also disclosed. Methods of preventing or inhibiting the growth of a hyperproliferative lesion in a subject that involve these therapeutic compositions and devices are also disclosed.
La présente invention a trait à des compositions et des procédés pour la prévention et l'inhibition de la croissance d'une lésion hyperproliférative chez un sujet comprenant un acide nucléique contenu dans une formulation solide ou semi-solide ou dans un dispositif d'administration transdermique ou transcutanée. L'invention a également trait à des compositions d'un acide nucléique capable de prévention ou d'inhibition de la croissance d'une lésion hyperproliférative chez un sujet comprenant un amplificateur de recaptage d'acide nucléique. L'invention a trait en outre à des procédés de prévention ou d'inhibition de la croissance d'une lésion hyperproliférative chez un sujet utilisant ces compositions et dispositifs thérapeutiques.
Chada Sunil
Clarke Peter
Menander Kerstin
Sobol Robert
Zhang Shuyuan
Bcf Llp
Introgen Therapeutics Inc.
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