Antimicrobial compositions comprising modified catechins and...

A - Human Necessities – 61 – K

Patent

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A61K 31/353 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2538106

A catechin is modified in at least one position (most preferably in the 3- position of the C-ring) to increase its lipophilicity. Contemplated catechins are demonstrated to have significantly improved antibacterial properties, likely due to catastrophic membrane damage.

L'invention concerne une catéchine modifiée dans au moins une position (de préférence en position 3 de la chaîne C), l'objectif étant d'en augmenter la lipophilicité. Les catéchines considérées ont démontré leurs propriétés antibactériennes largement améliorées, vraisemblablement suite à des dégâts catastrophiques sur la membrane.

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