Nucleic acid and corresponding protein entitled 205p1b5...

Details Nucleic acid and corresponding protein entitled 205p1b5... Nucleic acid and corresponding protein entitled 205p1b5...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/00 (2006.01) A61K 31/7088 (2006.01) A61K 35/14 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) A61K 49/00 (2006.01) C07K 14/47 (2006.01) C07K 14/82 (2006.01) C07K 16/18 (2006.01) C07K 16/30 (2006.01) C12N 5/10 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2458915

A novel gene (designated 205P1B5) and its encoded protein are described. While 205P1B5 exhibits tissue specific expression in normal adult tissue, it is aberrantly expressed in prostate cancer. Consequently, 205P1B5 provides a diagnostic, prognostic, prophlactic and/or therapeutic target for cancer. The 205P1B5 gene or fragment thereof, or its encoded protein or a fragment thereof, can be used to elicit an immune response.

L'invention concerne un nouveau gène (appelé 205P1B5) et la protéine qu'il code. Ledit gène 205P1B5 présente une expression spécifique aux tissus dans un tissu adulte normal, cette expression étant aberrante dans un cas de cancer de la prostate. Le gène 205P1B5 fournit ainsi une cible diagnostique, pronostique, prophylactique et/ou thérapeutique pour le cancer. Le gène selon l'invention ou un fragment de celui-ci, ou la protéine qu'il code ou un fragment de celle-ci, peut être utilisé pour déclencher une réponse immunitaire.

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