Sulfamides as gamma-secretase inhibitors

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 307/08 (2006.01) A61K 31/18 (2006.01) A61K 31/395 (2006.01) A61P 25/28 (2006.01) C07D 271/107 (2006.01) C07D 285/14 (2006.01) C07D 285/16 (2006.01) C07D 295/088 (2006.01) C07D 295/135 (2006.01)

Patent

CA 2427206

Novel sulfamides of formula (I) are disclosed. The compounds exert an inhibitory action on the processing of APP by gamma-secretase, and are therefore useful in the treatment or prevention of Alzheimer's disease.

L'invention concerne de nouveaux sulfamides représentés par la formule (I). Ces composés exercent une action inhibitrice sur la transformation de APP par la gamma-sectrétase, et sont par conséquent utiles pour le traitement ou la prévention de la maladie d'Alzheimer.

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