Pharmaceutical compositions and method of using same

A - Human Necessities – 61 – K

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A61K 31/7048 (2006.01) A61K 9/12 (2006.01) A61K 31/216 (2006.01) A61K 31/7034 (2006.01) A61P 31/04 (2006.01) A61P 31/12 (2006.01)

Patent

CA 2317453

The present invention provides a pharmaceutical composition comprising an extract or combination of extracts having an antiviral, antibacterial, or immunomodulating property, wherein the extract or combination of extracts is obtained from a combination of plants wherein at least one plant is selected from each of the genuses Labiatae, Caprifoliaceae, and Oleacea. A preferred extract is obtained from Radix Scutellaria, Flos Lonicera, and Fructus Forsythiae. The present invention further provides a pharmaceutical composition comprising baicalin, chlorogenic acid and forsythiaside in isolated and purified form. The present invention further provides certain novel derivatives of baicalin, chlorogenic acid and forsythiaside. The present invention additionally provides processes for preparing the extracts as well as baicalin, chlorogenic acid, and forsythiaside in isolated and purified forms.

Cette invention a trait à une composition pharmaceutique renfermant un extrait ou une combinaison d'extraits dotés de propriétés antivirales, antimicrobiennes ou immunomodulatrices. On obtient cet extrait ou la combinaison d'extraits en associant des végétaux, l'un au moins de ces végétaux étant sélectionné dans chacun des genres suivants: Labiatae, Caprifoliaceae et Oleaceae. L'un des extraits préférés est issu de Radix Scutellaria, Flos Lonicera et Fructus Forsythiae. L'invention, qui concerne également une composition pharmaceutique renfermant de la baïcaline, de l'acide chlorogénique et de la forsythiaside isolés et purifiés, porte, de surcroît, sur de nouveaux dérivés de baïcaline, d'acide chlorogénique et de forsythiaside ainsi que sur des procédés de mise au point d'extraits de baïcaline, d'acide chlorogénique et de forsythiaside isolés et purifiés.

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