Method for treating immune disorders

A - Human Necessities – 61 – K

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A61K 39/395 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2757933

The present invention relates to the treatment of B-cell mediated immune disorders such as rheumatoid arthritis, systemic lupus erythromatomus, diabetes mellitus, and multiple sclerosis. In particular, the present invention relates to the treatment of B-cell mediated immune disorders using antibodies which bind to membrane-bound free light chain expressed on the surface of plasma cell precursors.

La présente invention concerne le traitement de troubles immunitaires médiés par les lymphocytes B, tels que l'arthrite rhumatoïde, le lupus érythémateux systémique, le diabète sucré, et la sclérose multiple. En particulier, la présente invention concerne le traitement de troubles immunitaires médiés par les lymphocytes B au moyen d'anticorps qui se lient à une chaîne légère libre liée à une membrane, exprimée à la surface de précurseurs de plasmocytes.

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