Treating cancer with electric fields that are guided to...

A - Human Necessities – 61 – N

Patent

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A61N 1/32 (2006.01) A61N 1/40 (2006.01)

Patent

CA 2611398

Electric fields with certain characteristics have been shown to be effective at inhibiting the growth of cancer cells (and other rapidly dividing cells). However, when the cancer is located in a target region beneath the surface of a body, it can be difficult to deliver the beneficial fields to the target region. This difficulty can be surmounted by positioning a biocompatible field guide between the surface of the body and the target region, positioning electrodes on either side of the field guide, and applying an AC voltage with an appropriate frequency and amplitude between the electrodes. This arrangement causes the field guide to route the beneficial field to the target region. In an alternative embodiment, one of the electrodes is positioned directly on top of the field guide.

On a démontré que des champs électriques possédant certaines caractéristiques étaient efficaces pour inhiber la croissance de cellules cancéreuses (et d'autres cellules à division rapide). Toutefois, lorsque le cancer est situé dans une région cible se trouvant en-dessous de la surface du corps, il peut être difficile de distribuer des champs électriques bénéfiques pour la région cible. On peut surmonter cette difficulté par positionnement d'un guide de champ biocompatible entre la surface du corps et la région cible, positionnement d'électrodes sur l'un ou l'autre côté du guide de champ et application d'une tension c.a. à une fréquence et une amplitude appropriées entre les électrodes. Cet agencement permet au guide de champ d'acheminer le champ bénéfique sur la région cible. Dans un autre mode de réalisation, l'une des électrodes est positionnée directement sur la partie supérieure du guide de champ.

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