Chiral synthesis for producing...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/08 (2006.01) C07D 207/16 (2006.01) C07D 487/08 (2006.01) C07D 491/04 (2006.01) C07D 491/044 (2006.01) C07F 7/10 (2006.01)

Patent

CA 2016706

ABSTRACT Title: CHIRAL SYNTHESIS FOR PRODUCING 1-AZABICYCLO[2.2.1] HEPTANE-3-CARBOXYLATES A process for preparing substantially pure enantiomers of formula (I) Image (I) where the * represents a chiral centre, x is 0 or 1, in exo-, endo- or a mixture of exo- and endo- forms; and R is hydrogen, alkyl or aralkyl, via diastereomers of formula (IIA) or (IIB): Image Image IIA IIB

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